Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Deadline

Jul 1, 2028 (616 days left)

Who can apply

Others

Award range

$300,000 to $5.0 million

Expected awards

Not stated

Total program funding

Not stated

Your own money required

No cost sharing or matching required

Opportunity number

PAR-27-022

Posted

Jun 25, 2026

Assistance listing

93.867

More on who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

What it funds

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program are required to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on the total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments.

What to do next

1. Open the official notice on Grants.gov and download the full announcement (the NOFO) and any attachments.
2. Check you can apply: the eligible applicants above, and any detail in the notice's eligibility section.
3. Register your organization in SAM.gov (choose "all awards") and create a Grants.gov account; allow several weeks the first time.
4. Apply through Grants.gov exactly as the notice says, before Jul 1, 2028. Late applications are usually not accepted.

New to this? Applying for a federal grant, step by step · Register to apply · How to read the notice · Write the narrative · Build the budget · Agency contact: odsig@mail.nih.gov

From Grants.gov's official daily extract of Oct 25, 2026. The notice on Grants.gov and its attachments are what count. UX Contract is independent and not a government website.