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FORECAST · COOPERATIVE AGREEMENT

Restoring Joint Health and Function to Reduce Pain (RE-JOIN) 2.0

National Institutes of Health · Health

Forecast. The agency expects to post this grant around Oct 1, 2026 (fiscal year 2026). Dates and amounts are estimates until the notice posts.
Expected deadline
Not stated
Who can apply
Others
Award range
Not stated
Expected awards
8
Total program funding
Not stated
Your own money required
No cost sharing or matching required
Opportunity number
RFA-AR-26-006
Posted
Jan 22, 2026
Assistance listing
93.846

More on who can apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

What it funds

The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), in conjunction with other NIH Institutes and Centers (ICs) as a part of the congressionally mandated NIH Helping to End Addiction Long Term (HEAL) initiative intends to publish a Notice of Funding Opportunity (NOFO) to leverage and accelerate the progress achieved in the Restoring Joint Health and Function to Reduce Pain (RE-JOIN) Consortium.The NOFO aims to more fully refine and map the innervation of the different articular and peri-articular tissues that collectively form the joint (including bone, cartilage, synovium, joint capsule, ligament, tendon, fascia and muscle), by sensory neurons that mediate the sensation of pain.The NOFO seeks to expand initial and ongoing efforts by:Enhancing clinical pain phenotyping with multimodal profiling of new and expanded patient samples across life span and disease conditions (i.e., other musculoskeletal and/or rheumatic conditions associated with joint pain beyond knee and temporomandibular joint (TMJ)).Expanding to new preclinical and New Approach Methodologies (NAMs) in modeling joint disease.Preclinical testing of novel joint-targeted candidates identified in RE-JOIN 1.0.Focusing on peri-articular tissues in joint pain, such as vasculature, synovium, adipose, myofascial tissue, etc.Prioritizing secondary analysis of datasets and/or validation of methods and approaches in human samples.Improve data integration by developing/enhancing joint atlases that will enable integration of imaging and molecular datasets.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful multidisciplinary collaborations and responsive projects. Investigators with expertise and insi…

Open the official notice on Grants.gov ↗

What to do next

  1. This is a forecast: the agency expects to post the full notice later. Open it on Grants.gov and subscribe there to be told when it posts.
  2. Get your SAM.gov registration ("all awards") and Grants.gov account active now; both take time.
  3. Use the forecast's award range and eligibility to decide whether to prepare.
  4. Watch for the notice; the dates here are estimates and can change.

New to this? Applying for a federal grant, step by step · Register to apply · How to read the notice · Write the narrative · Build the budget · Agency contact: NIAMS_PAIN@mail.nih.gov

From Grants.gov's official daily extract of Oct 25, 2026. The notice on Grants.gov and its attachments are what count. UX Contract is independent and not a government website.

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