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ACCEPTING APPLICATIONS · GRANT

Pilot and Feasibility Studies in Preparation for Substance Use and HIV Prevention Intervention and Services Research Trials (R34 Clinical Trial Optional)

National Institutes of Health · Health

Accepting applications. The agency is taking applications now through Grants.gov.
Deadline
Jul 16, 2029 (995 days left)
Who can apply
Others
Award range
Up to $450,000
Expected awards
Not stated
Total program funding
Not stated
Your own money required
No cost sharing or matching required
Opportunity number
PAR-28-093
Posted
Oct 19, 2026
Assistance listing
93.681

More on who can apply

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/

What it funds

The purpose of this notice of funding opportunity (NOFO) is to support pilot and feasibility studies to inform the design and conduct of efficacy, effectiveness, and/or services research trials. Topics may include: 1) developing interventions to prevent substance use, misuse, or progression to substance use disorder; 2) prevention, treatment, or recovery services research, including research addressing comorbid pain and medical and mental health disorders; and 3) HIV eradication research, including implementation science, prevention, treatment and recovery in substance use settings/populations.

Open the official notice on Grants.gov ↗

What to do next

  1. Open the official notice on Grants.gov and download the full announcement (the NOFO) and any attachments.
  2. Check you can apply: the eligible applicants above, and any detail in the notice's eligibility section.
  3. Register your organization in SAM.gov (choose "all awards") and create a Grants.gov account; allow several weeks the first time.
  4. Apply through Grants.gov exactly as the notice says, before Jul 16, 2029. Late applications are usually not accepted.

New to this? Applying for a federal grant, step by step · Register to apply · How to read the notice · Write the narrative · Build the budget · Agency contact: pilotstudies@mail.nih.gov

From Grants.gov's official daily extract of Oct 25, 2026. The notice on Grants.gov and its attachments are what count. UX Contract is independent and not a government website.

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