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FORECAST · COOPERATIVE AGREEMENT

Controlled Clinical Trials on Long-Term Effects of Nutritional Interventions on the Progression of Risk Factors for Age-Related Chronic Conditions Over the Life Span and Their Age of Onset

National Institutes of Health · Health

Forecast. The agency expects to post this grant around Jun 25, 2026 (fiscal year 2027). Dates and amounts are estimates until the notice posts.
Expected deadline
Not stated
Who can apply
Others
Award range
Not stated
Expected awards
Not stated
Total program funding
Not stated
Your own money required
No cost sharing or matching required
Opportunity number
PAR-26-065
Posted
Jan 29, 2026
Assistance listing
93.866

More on who can apply

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations.

What it funds

The National Institute on Aging (NIA) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for randomized controlled clinical trials on long-term effects of nutritional interventions on the progression of risk factors for age-related chronic conditions over the life span and their age of onset.Although considerable information is available on health benefits and risks of a variety of nutritional factors (e.g., macronutrients, overall caloric intake, differing nutrient sources) there remains a need for better understanding of long-term benefits and potential risks of differing nutritional factors and dietary practices to maintain health across the full range of the life span. Rigorous understanding of these effects requires long-term controlled clinical trials of preventive interventions in younger and/or older persons. Given the rates of risk factor progression in younger persons and of accumulation of morbidities in later life, many such trials will require long-term intervention durations and follow-up of at least 5 years to provide sufficient power and evidence of their long-term effects. In order to support projects of sufficient duration to provide for start-up, enrollment, follow-up, and outcome data analyses in such trials, applications in response to this NOFO may propose projects of up to seven years in length.Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO intends to utilize the U19 activity code. Investigators with expertise and insights into this area of aging research are encouraged to begin to consider applying for this new NOFO.

Open the official notice on Grants.gov ↗

What to do next

  1. This is a forecast: the agency expects to post the full notice later. Open it on Grants.gov and subscribe there to be told when it posts.
  2. Get your SAM.gov registration ("all awards") and Grants.gov account active now; both take time.
  3. Use the forecast's award range and eligibility to decide whether to prepare.
  4. Watch for the notice; the dates here are estimates and can change.

New to this? Applying for a federal grant, step by step · Register to apply · How to read the notice · Write the narrative · Build the budget · Agency contact: NIA-NOFO-Scientific@nih.gov

From Grants.gov's official daily extract of Oct 25, 2026. The notice on Grants.gov and its attachments are what count. UX Contract is independent and not a government website.

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