FORECAST · GRANT
BRAIN Initiative: Development and Validation of Novel Tools and New Approaches for Neuroscience Research
- Expected deadline
- Not stated
- Who can apply
- Others
- Award range
- Not stated
- Expected awards
- 10
- Total program funding
- $12 million
- Your own money required
- No cost sharing or matching required
- Opportunity number
- RFA-MH-28-110
- Posted
- Jun 24, 2026
- Assistance listing
- 93.242
More on who can apply
Other Eligible ApplicantsEligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).
What it funds
The Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research to develop novel tools and approaches that enable the interrogation of cell-specific and circuit-specific processes in the central nervous system. This NOFO consolidates three current BRAIN Initiative tool development programs.Projects that focus on developing a broad range of new research tools to delineate anatomical and functional connections between cells and circuits, and to expand our knowledge of brain architecture and function are encouraged, such as projects that:Develop novel tools to characterize/define cell-types, circuits, and cellular components in the nervous system with greater selectivity and sensitivity, including:new genetic or non-genetic technologies/approaches (for delivering genes, proteins, and chemicals to access and/or manipulate cells of interest)novel sensors or tracers for imaging or monitoring molecules, structures, and activities within single cells and circuits with significant advances in sensitivity, selectivity, or spatiotemporal resolutionDevelop new technologies and novel approaches for recording and modulation of neural cells and circuits, including:approaches to address major challenges and enable transformative understanding of dynamic signaling in the central nervous systemapproaches that utilize any modality, such as optical, electrical, magnetic, or acoustic recording/manipulationapproaches to target neuronal electrical signals or other forms of neural activity, including intracellular signaling and engagement of non-neuronal cells in circuit function.Projects at broad stages of development are supported, from unique and innovative technologies that a…
Open the official notice on Grants.gov ↗What to do next
- This is a forecast: the agency expects to post the full notice later. Open it on Grants.gov and subscribe there to be told when it posts.
- Get your SAM.gov registration ("all awards") and Grants.gov account active now; both take time.
- Use the forecast's award range and eligibility to decide whether to prepare.
- Watch for the notice; the dates here are estimates and can change.
New to this? Applying for a federal grant, step by step · Register to apply · How to read the notice · Write the narrative · Build the budget · Agency contact: BRAINTools@nih.gov.
From Grants.gov's official daily extract of Oct 25, 2026. The notice on Grants.gov and its attachments are what count. UX Contract is independent and not a government website.